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Contents
KEY FEATURES VI | PREFACE IX | ACKNOWLEDGMENTS XI
1 Histology & Its Methods of Study 1
Preparation of Tissues for Study 1 Light Microscopy 4 Electron Microscopy 8 Autoradiography 9 Cell & Tissue Culture 10 Enzyme Histochemistry 10 Visualizing Specific Molecules 10 Interpretation of Structures in Tissue Sections 14
Summary of Key Points 15 Assess Your Knowledge 16
2 The Cytoplasm 17
Cell Differentiation 17 The Plasma Membrane 17 Cytoplasmic Organelles 27 The Cytoskeleton 42 Inclusions 47 Summary of Key Points 51 Assess Your Knowledge 52
3 The Nucleus 53
Components of the Nucleus 53 The Cell Cycle 58 Mitosis 61
Stem Cells & Tissue Renewal 65
Meiosis 65
Apoptosis 67
Summary of Key Points 69
Assess Your Knowledge 70
4 Epithelial Tissue 71
Characteristic Features of Epithelial Cells 72
Specializations of the Apical Cell Surface 77
Types of Epithelia 80
Transport Across Epithelia 88
Renewal of Epithelial Cells 88
Summary of Key Points 90
Assess Your Knowledge 93
5 Connective Tissue 96
Cells of Connective Tissue 96 Fibers 103
Ground Substance 111 Types of Connective Tissue 114 Summary of Key Points 119 Assess Your Knowledge 120
6 Adipose Tissue 122
White Adipose Tissue 122 Brown Adipose Tissue 126 Summary of Key Points 127 Assess Your Knowledge 128
7 Cartilage 129
Hyaline Cartilage 129 Elastic Cartilage 133 Fibrocartilage 134
Cartilage Formation, Growth, & Repair 134 Summary of Key Points 136 Assess Your Knowledge 136
8 Bone 138
Bone Cells 138 Bone Matrix 143 Periosteum & Endosteum 143 Types of Bone 143 Osteogenesis 148 Bone Remodeling & Repair 152 Metabolic Role of Bone 153 Joints 155
Summary of Key Points 158 Assess Your Knowledge 159
9 Nerve Tissue & the Nervous System 1 61
Development of Nerve Tissue 161 Neurons 163
Glial Cells & Neuronal Activity 168 Central Nervous System 175 Peripheral Nervous System 182
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