Kathy L. Perkins
I. Well Child Care—General Concepts 3
II. Growth 4
III. Immunizations 9
IV. Well Child Screening 13
V. Circumcision 16
VI. Pediatric Dental Care 17
VII. Developmental Screening 19
VIII. Anticipatory Guidance 19 Review Test 23
I. Normal Developmental Milestones 29
II. Disorders of Development 35
III. Dysfunctions of Attention (Attention De fi cit/Hyperactivity
IV. Specifi c Sensory Impairments 41
V. Common Behavioral Concerns 43
Lloyd J . Brown
I. Adolescent Growth and Development 55
II. Adolescent Health Screening 60
III. Depression and Suicide 62
IV. Substance Abuse 64
V. Obesity and Eating Disorders 65
VI. Female Reproductive Health Issues 67
VII. Sexually Transmitted Diseases (STDs) 69
VIII. Menstrual Disorders 75
IX. Reproductive Health Issues in Males 79 Review Test 82
Part 2 Specific Problems
4 Neonatology 89
Marta Rogido, Augusto Sola, and Lee Todd Miller
I. Evaluation of the Newborn 89
II. Abnormalities of Maturity 94
III. Growth Abnormalities 95
IV. Cyanosis 96
V. Respiratory Distress 97
VI. Respiratory Distress Syndrome (RDS) 98
VII. Persistent Pulmonary Hypertension of the Newborn (PPHN) 100
VIII. Meconium Aspiration Syndrome (MAS) 101
IX. Apnea of Prematurity 101
X. Neonatal Jaundice 102
XI. Infants of Drug-Abusing Mothers 105
XII. Surgical Conditions of the Newborn 106
XIII. Hypoglycemia 109
XIV. Infants of Diabetic Mothers (IDMs) 110
XV. Polycythemia 111
Review Test 112
5 Genetic Disorders and Inborn Errors
of Metabolism 119
Sharon L. Young
I. Inheritance Patterns 119
II. Fetal Evaluation and Prenatal Diagnosis 121
III. Common Genetic Disorders 121
IV. Inborn Errors of Metabolism (IEM) 130
V. Defects in Amino Acid Metabolism 133
VI. Defects in Carbohydrate Metabolism 135
VII. Fatty Acid Oxidation Defects 136
VIII. Mitochondrial Disorders 137
IX. Lysosomal Storage Diseases 137
X. Defects in Heme Pigment Biosynthesis (Porphyrias) 138
XI. Disorders of Metal Metabolism 139 Review Test 140
6 Endocrinology 147
Ronald A. Nagel and Lee Todd Miller
I. Short Stature 147
II. Disorders of Puberty 152
III. Ambiguous Genitalia 156
IV. Disorders of the Adrenal Gland 160
V. Diabetes Mellitus 163
VI. Type 1 Diabetes Mellitus (Type 1 DM) 163
VII. Type 2 Diabetes Mellitus (Type 2 DM) 165
Vili. Diabetic Ketoacidosis (DKA) 166
IX. Thyroid Disorders 167
X. Bone Mineral Disorders 170
XI. Diabetes Insipidus (DI) 173
XII. Hypoglycemia 174 Review Test 176
7 Infectious Diseases 181
Deborah Lehman, Srinath Sanda, and Nirali P. Singh
I. General Approach to the Child with Possible Infection 181
II. Evaluation of the Child with Fever 182
III. Fever of Unknown Origin (FUO) 184
IV. Meningitis 186
V. Upper Respiratory Infections 190
VI. Middle and Lower Respiratory Infections 194
VII. Cervical Lymphadenitis 194
VIII. Parotitis 195
IX. Skin and Soft Tissue Infections 196
X. Bone and Joint Infections 199
XI. Diarrhea 199
XII. Urinary Tract Infections 202
XIII. Specific Viral Infections 202
XIV. Specifi c Fungal Infections 208
XV. Specifi c Parasitic Infections 209
XVI. Specific Helminth Infections 212
XVII. Miscellaneous Infections 214 Review Test 218
8 Cardiology 225
David A. Ferry and David Seung Chun
I. Congestive Heart Failure (CHF) 225
II. Innocent Cardiac Murmurs 226
III. Acyanotic Congenital Heart Disease 227
IV. Cyanotic Congenital Heart Disease 236
V. Acquired Heart Disease 243
VI. Dysrhythmias 249
VII. Chest Pain 251 Review Test 253
9 Pulmonology 259
Lauren J. Witcoff
I. Anatomy and Physiology of the Respiratory System 259
II. Clinical Assessment of Pulmonary Disease 260
III. Infectious Disorders of the Respiratory Tract 261
IV. Noninfectious Disorders of the Respiratory Tract 268 Review Test 277
10 Gastroenterology 283
Tiffany Merrill Becker, Frederick D. Watanabe, and Lloyd J. Brown
I. Nutrition 283
II. Malabsorption 284
III. Gastroesophageal Reflux 288
IV. Intestinal Anatomic Obstructions That Result in Vomiting 290
V. Acute Abdominal Pain 294
VI. Chronic Abdominal Pain 298
VII. Constipation and Encopresis 300
VIII. Diarrhea 302
IX. In fl ammatory Bowel Disease 302
X. Gastrointestinal Bleeding 305
XI. Liver Abnormalities and Hepatitis 308 Review Test 318
11 Nephrology and Urology 325
E lain e S. Kam il an d Lee Todd Miller
I. Fluids, Electrolytes, and Dehydration 325
II. Hematuria 327
III. Proteinuria 328
IV. Glomerulonephritis 330
V. Nephrotic Syndrome (NS) 334
VI. Hemolytic Uremic Syndrome (HUS) 336
VII. Hereditary Renal Diseases 337
VIII. Hypertension 339
IX. Renal Tubular Acidosis (RTA) 342
X. Renal Failure 344
XI. Structural and Urologic Abnormalities 347
XII. Urolithiasis 348
XIII. Urinary Tract Infection (UTI) 350 Review Test 353
12 Neurology 361
Charles E. Niesen
I. The Hypotonic Infant 361
II. Hydrocephalus 365
III. Spina Bifida 366
IV. Approach to the Comatose Patient 368
V. Seizure Disorders of Childhood 371
VI. Headaches in Childhood 376
VII. Approach to Unsteady Gait 379
VIII. Movement Disorders 381
IX. Duchenne and Becker Muscular Dystrophies (DMD, BMD) 383
X. Myasthenia Gravis 3 85 Review Test 387
13 Hematology
Annette B. Salinger and Lloyd J. Brown
I. Anemia 393
II. Pancytopenia 404
III. Polycythemias 406
IV. Disorders of Hemostasis 407
V. Neutropenia 415
Review Test 417
14 Oncology
Carole Hurvitz, Liliana Sloninsky, Margaret Sanford, and Lloyd J . Brown
I. General Considerations 423
II. Leukemias 424
III. Lymphomas 429
IV. Brain Tumors 431
V. Renal and Suprarenal Tumors 433
VI. Soft Tissue Tumors 436
VII. Bone Tumors 437
VIII. Liver Tumors 439
IX. Retinoblastoma 439
X. Germ Cell Tumors 439
XI. Langerhans Cell Histiocytosis (LCH) 440 Review Test 442
15 Allergy and Immunology
Elizabeth A. Mumper and Frank T. Saulsbury
I. Anaphylaxis 447
II. Allergic Rhinitis 447
III. Atopic Dermatitis 450
IV. Food Allergy 451
V. Insect Venom Allergy 452
VI. Urticaria (Hives) 452
VII. Drug Allergy 453
VIII. Asthma 454
IX. Immunology Overview 454
X. Disorders of Lymphocytes 455
XI. Disorders of Granulocytes 459
XII. Disorders of the Complement System 461 Review Test 462
16 Rheumatology
Jerome K. Wang, Lee Todd Miller, and Frank T. Saulsbury
I. Henoch-Schonlein Purpura 467
II. Kawasaki Disease (Mucocutaneous Lymph Node Syndrome)
III. Juvenile Rheumatoid Arthritis (JRA) 471
IV. Systemic Lupus Erythematosus (SLE) 474
V. Dermatomyositis 476
VI. Rheumatic Fever 478
VII. Lyme Disease 480
VIII. Other Rheumatologic Conditions of Childhood 482 Review Test 484
17 Orthopedics
Sharon L. Young
I. Upper Extremity 489
II. Spine 490
III. Hip 494
IV. Lower Extremity 500
V. Common Fractures 504
Review Test 510
18 Ophthalmology
Kenneth W. Wright and Robert K. Rhee
I. Ocular Examination and Vision Screening 515
II. Normal Visual Development and Amblyopia 515
III. Conjunctivitis and the Red Eye 517
IV. Abnormal Tearing 522
V. Ocular Trauma 523
VI. Congenital Glaucoma 524
VII. Retinopathy of Prematurity (ROP) 525
VIII. Leukocoria 526
IX. Strabismus 527 Review Test 528
19 Dermatology
Harry W. Saperstein and Lloyd J. Brown
I. General Concepts 533
II. Newborn Skin Diseases 535
III. Inflammatory Disorders 535
IV. Hypersensitivity Disorders 538
V. Infections of the Skin 538
VI. Pigmentary Disorders 545
VII. Disorders of the Hair 547
VIII. Acne Vulgaris 548 Review Test 549
20 Emergency Medicine
Calvin G. Lowe
I. Infant and Child Cardiopulmonary Resuscitation (CP R) 553
II. Shock 554
III. Trauma 556
IV. Burns 559
V. Near Drowning 561
VI. Child Abuse 562
VII. Sudden Infant Death Syndrome (SIDS) 565
VIII. Poisonings 566
IX. Mammalian Bites 574
X. Biologic Poisonings (Venoms) 575 Review Test 578
Comprehensive Examination 583
Index 613